IGF2R (insulin-like growth factor 2 receptor)
نویسندگان
چکیده
منابع مشابه
SacI RFLP in the insulin-like growth factor 2 receptor gene (IGF2R) on human chromosome 6q.
R.Hauptschein, R. Dalla-Favera* and G.Gaidano Department of Pathology and Cancer Center, College of Physicians & Surgeons, Columbia University, New York, NY 10032, USA A Pvull RFLP at D6S114E locus in the HLA region (RING4 locus) F.Muntoni, R.Lampis, F.Frau, LArgiolas, M.R.Murru, G.Costa and M.Congia Laboratorio di Ematologia e Patologia Molecolare, CNR e lstituto di Clinica e Biologia dell'Eta...
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Insulin-like growth factor-I receptor (IGF-IR) and its ligands, IGF-I and IGF-II, are up-regulated in a variety of human cancers. In tumors, such as colorectal, non-small cell lung, ovarian, and pediatric cancers, which may drive their own growth and survival through autocrine IGF-II expression, the role of IGF-IR is especially critical. Here, we present a novel small-molecule IGF-IR kinase inh...
متن کاملThe type 1 insulin-like growth factor receptor pathway.
Research conducted over the past two decades has shown the importance of the type 1 insulin-like growth factor receptor (IGF1R) in tumorigenesis, metastasis, and resistance to existing forms of cancer therapy. The IGF1R itself has only recently been accepted as a credible treatment target, however, perhaps reflecting the potential problems for drug design posed by normal tissue IGF1R expression...
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ژورنال
عنوان ژورنال: Atlas of Genetics and Cytogenetics in Oncology and Haematology
سال: 2011
ISSN: 1768-3262
DOI: 10.4267/2042/38064